CLCS occupies 4400 square feet on the 6th floor of the Wohl Clinic Building and 688 square feet on the 5th floor of the connected Wohl Hospital Building at Washington University School of Medicine. The work area is under double lock with Washington University providing 24-hr security and monitoring. Laboratory Services accepts and logs in samples, reports data and assists clients. A sample collection kit preparation/shipping area is directly adjacent and is used to support central lab activity for multicenter clinical trials and send out testing.
CLCS has a proprietary laboratory information system known as CLAS, Core Laboratory Access System. In contrast to a typical hospital laboratory that has relatively fixed computer needs, CLAS is focused on research testing and allows CLCS to adapt to the special requirements of its clients. CLAS runs on a virtual server located in the Department of Medicine Computing Facility. Data are backed up nightly and a policy is in place for data handling during computer downtime. Computer services are HIPAA compliant and part of the Washington University intranet. Analytical instruments are interfaced directly with CLAS. After release, data are transmitted in a variety of electronic formats to our clients. A dedicated long-term storage freezer room with 21 -70° C freezers is alarmed and monitored and has a high-capacity air handler to dissipate the increased heat load.
Core Lab has all common types of clinical chemistry analyzers. The following instruments are owned by CLCS and available for use:
- Roche Diagnostics c501 chemistry analyzer
- Beckman LH500 hematology analyzer
- Siemens Immulite 1000 immunoanalyzer
- Roche Diagnostics Elecsys 2010 immunoanalyzer
- Singulex Erenna immunoanalyzer (digital single molecule counting)
- ICN Biomedical 10/600 Plus gamma counter
- Titertek Plus gamma counter
- Bio-Tek ELx 800 ELISA plate reader
- Bio-Tek Powerwave 200 plate reader
Core Lab can run kits designed for these instruments as well as radioimmunoassays and most plate-based ELISA tests.